Soyuz TM-21 was the 21st mission and the 18th long-duration expedition to Mir space station. It was also a part of the US/Russian Shuttle-Mir Program.
The mission began on March 14, 1995, 06:11:34 UTC, launching Commander Vladimir Dezhurov, Flight Engineer Gennady Strekalov and Research Cosmonaut Norman Thagard (who became the first American to ride the Soyuz) into orbit. They docked with Mir two days later. During their stay there, cosmonauts performed several EVAs to prepare for the docking of the new Spektr module. Station crew was visited by several Progress resupply spacecrafts, and welcomed aboard the STS-71 with the 19th expedition crew.
Crews exchanged vehicles, and members of the 18th expedition returned aboard STS-71, landing safely back on Earth on 7 July 1995, 14:55:28 UTC. Soyuz TM-21 brought back the 19th expedition later on September 11, 1995, 06:52:40 UTC.